India has just seen the launch of a groundbreaking Presvu eye drops that could eliminate the need for reading glasses for millions of people. Developed by Entod Pharmaceuticals, the eye drop, branded as PresVu, is specifically designed to treat presbyopia—an age-related condition that causes blurry vision, typically affecting individuals over 40.
A New Solution for Age-Related Vision Loss
PresVu contains 1.25% pilocarpine hydrochloride, a plant-derived compound with a long history of treating various eye conditions. With the recent approval from the Drugs Controller General of India (DCGI), this eye drop is set to become India’s first presbyopia treatment of its kind. It’s designed to help those who struggle to focus on nearby objects, offering a convenient alternative to traditional reading glasses.
Presvu Eye Drops Are Affordable and Accessible
The eye drops will be available across India by October, with a single vial priced at Rs 345, designed to last about a month. The launch of PresVu Eye drops follows extensive research and development by Entod Pharmaceuticals, which began in 2019. Nikhil Masurkar, CEO of Entod Pharmaceuticals, noted that nearly 45% of Indians above the age of 40 suffer from presbyopia, highlighting the potential impact of this new treatment.
How It Works and Who It’s For
Data from phase 3 clinical trials, conducted on 250 patients across 10 sites, show that PresVu Eye Drops works best for individuals aged 40 to 55 with mild-to-intermediate presbyopia. The eye drops offer temporary correction of vision problems, with the effect lasting about six hours after application. One drop in each eye is recommended daily, with an additional drop permissible three to six hours later for extended relief.
Clinical Benefits and Safety
According to Dr. Dhananjay Bakhle, a senior pharmacologist and advisor to Entod Pharmaceuticals, PresVu Eye drops offers a non-invasive option to improve near vision, providing an alternative to reading glasses. The eye drops are said to start working within 15 minutes, with full benefits typically visible after 15 days of consistent use.
Tailored for Indian Eyes
Unlike similar products available abroad, such as Vuity in the U.S., PresVu has been specifically formulated to suit Indian eyes, which tend to have more pigmented irises. The proprietary formulation not only aids in vision correction but also offers the added benefit of lubricating the eyes. Entod Pharmaceuticals has applied for a patent on both the formulation and manufacturing process of PresVu.
Potential Side Effects and Safety Monitoring
While PresVu offers a promising alternative to reading glasses, it’s essential to use it under the supervision of an ophthalmologist. The Central Drugs Standard Control Organisation (CDSCO) has requested phase 4 data collection post-commercialization to monitor the drug’s safety. The US FDA, which approved a similar product, Vuity, lists potential side effects such as headaches, red eyes, blurred vision, and eye irritation, though these were reported in less than 5% of clinical trial participants.
A Game-Changer for Vision Care
PresVu is set to transform the way presbyopia is treated in India, offering a convenient, non-invasive solution to age-related blurry vision. With the launch of this eye drop, many individuals can look forward to a life without the constant need for reading glasses, improving their daily lives and activities. However, as with any new treatment, it’s crucial to consult with a healthcare provider to ensure it’s the right option for you.